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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
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Predicting hospitalization and mortality in patients with heart failure: The BARDICHE-index

Nicole H M K Uszko-Lencer1, Lutz Frankenstein2, Martijn A Spruit3

  • 1Department of Cardiology, CARIM; Maastricht University Medical Centre + (MUMC+), Maastricht, The Netherlands; Department of Research & Education, CIRO, Centre of Expertise for Chronic Organ Failure, Horn, The Netherlands.

International Journal of Cardiology
|December 5, 2016
PubMed

Insights

The BARDICHE-index offers a simple way to predict outcomes for chronic heart failure (CHF) patients. This new tool helps assess mortality and hospitalization risks, improving patient care.

Area of Science:

  • Cardiology
  • Medical Prognostics
  • Clinical Research

Background:

  • Prognostic assessment in chronic heart failure (CHF) is challenging.
  • Existing risk scores are often complex to apply in clinical practice.
  • A need exists for a user-friendly prognostic tool for CHF patients.

Purpose of the Study:

  • To develop and validate a simple, multidimensional prognostic index for CHF patients.
  • To create a tool that utilizes easily obtainable prognostic factors.
  • To improve risk stratification and patient management in CHF.

Main Methods:

  • Developed the BARDICHE-index using factors: Body mass index, Age, Resting systolic blood pressure, Dyspnea, NT-proBNP, Creatinine clearance (Cockroft-Gault), Heart rate, and Exercise capacity (6-min walk test).
  • Validated the index in 1811 patients from two prospective CHF cohorts with a median follow-up of 887 days.
  • Assessed 5-year all-cause survival, survival without all-cause hospitalization, and survival without CHF-related hospitalization.

Main Results:

  • Significant differences in mortality and hospitalization rates were observed across BARDICHE-risk groups (low, medium, high).
  • The index demonstrated strong predictive power for all-cause mortality (HR=3.63 per group) and hospitalization (HR=2.00-3.43 per group).
  • Prognostic accuracy was independent of left ventricular ejection fraction (LVEF) and gender.

Conclusions:

  • The BARDICHE-index is a validated, simple prognostic tool for chronic heart failure patients.
  • It effectively predicts mortality and hospitalization risks.
  • The index provides valuable prognostic information independently of LVEF.
Abstract

Keywords:
Chronic heart failurePrognostic modelSurvival

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