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Maximizing the Impact of Physiologically Based Oral Absorption Modeling and Simulation

John I Chung1, Ron C Kelly1, Jan Wahlstrom2

  • 1Amgen Inc., Drug Product Technologies, Thousand Oaks, California 91320.

Journal of Pharmaceutical Sciences
|December 5, 2016
PubMed
Summary

Physiologically based oral absorption modeling and simulation (PBMS) offers efficient and cost-effective drug development. This approach helps accelerate the delivery of innovative medicines amid intense pharmaceutical competition.

Keywords:
dispositionformulationgastrointestinalin silico modelingmathematical modeloral absorptionoral drug deliveryphysiologically based pharmacokinetic modeling

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