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Update on Blindness Due to Retinopathy of Prematurity Globally and in India
Hannah Blencowe1, Sarah Moxon, Clare Gilbert
1Maternal Reproductive and Child Health (MARCH) Centre, and *International Centre for Eye Health, Department of Clinical Research; London School of Hygiene and Tropical Medicine, London, UK Correspondence to: Dr Hannah Blencowe, Maternal Adolescent Reproductive and Child Health (MARCH) Centre, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT. Hannah.Blencowe@lshtm.ac.uk.
Insights
Retinopathy of prematurity (ROP) causes blindness in preterm infants, especially in middle-income nations. Improving neonatal care quality and ROP screening is crucial to prevent vision loss worldwide.
Area of Science:
- Neonatal ophthalmology
- Public health
- Pediatric critical care
Background:
- Retinopathy of prematurity (ROP) is a significant cause of preventable blindness and visual impairment in premature infants.
- Global incidence of ROP-related blindness was 32,200 cases in 2010, disproportionately affecting middle-income countries.
- Expansion of neonatal care in some regions has outpaced quality improvements, leading to increased ROP burden.
Purpose of the Study:
- To highlight the global impact of Retinopathy of prematurity (ROP).
- To emphasize the critical role of neonatal care quality and oxygen management in ROP prevention.
- To advocate for increased investment in eye-care provider training and ROP screening/treatment programs.
Main Methods:
- This study is a review and analysis of global ROP incidence data.
- It synthesizes information on the relationship between neonatal care quality and ROP outcomes.
- It examines the specific burden of ROP in India and implications for scaling neonatal services.
Main Results:
- In 2010, 32,200 new cases of blindness and visual impairment due to ROP were estimated globally.
- India represented nearly 10% of the global ROP burden, with 5,000 severe cases and 2,900 visually impaired survivors.
- Substandard neonatal care quality and inadequate nursing skills contribute significantly to ROP incidence.
Conclusions:
- Effective ROP management requires high-quality neonatal care, including safe oxygen protocols and skilled personnel.
- Investment in training eye-care providers and scaling up screening and treatment is essential.
- Without improved standards, the incidence of ROP-related visual impairment will rise globally, particularly in developing nations.
Abstract:
Retinopathy of prematurity (ROP), a well-known complication of preterm birth that can result in avoidable blindness and visual impairment, is especially sensitive to the quality of neonatal inpatient care and appropriate, well-monitored oxygen. In 2010, the annual incidence of blindness and visual impairment from ROP was estimated to be 32,200 cases worldwide. The greatest burden is seen in middle-income countries, particularly where coverage of neonatal inpatient care has expanded without due attention to the quality of care provided, and the neonatal nursing skills and training of those providing this care. India accounted for nearly 10% of all estimated worldwide visual impairment following ROP in 2010, with at least 5,000 developing severe disease and 2,900 children surviving with visual impairment related to ROP. Screening all those at risk and providing treatment for those with severe disease will require investment to increase the capacities and competencies of eye-care providers. Scale-up of neonatal services must be coupled with implementation of standards for high quality care, including safe oxygen management, and detection and treatment of ROP. Otherwise the number of children surviving preterm birth with visual impairment secondary to ROP will continue to increase in India and worldwide.
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