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Retinopathy of Prematurity: Clinical Features, Classification, Natural History, Management and Outcome

Parag K Shah1, Vishma Prabhu, Ratnesh Ranjan

  • 1Pediatric Retina and Ocular Oncology Department, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Coimbatore, Tamilnadu, India. Correspondence to: Dr Parag K Shah, Department of Pediatric Retina and Ocular Oncology, Aravind Eye Hospital, Avinashi Road, Coimbatore 641 014, Tamil Nadu, India. drshahpk2002@yahoo.com.

Indian Pediatrics
|December 5, 2016
PubMed

Insights

Retinopathy of prematurity (ROP) is a leading cause of childhood blindness. This review details ROP classification and treatment, emphasizing timely screening for preterm infants to prevent vision loss.

Area of Science:

  • Ophthalmology
  • Neonatology
  • Public Health

Background:

  • Retinopathy of prematurity (ROP) is a significant, preventable cause of childhood blindness.
  • Understanding ROP classification and treatment is crucial for effective management.

Purpose of the Study:

  • To provide an updated review on the classification and treatment of retinopathy of prematurity.
  • To guide pediatricians in managing ROP and to inform screening protocols.

Main Methods:

  • A literature search was conducted using PubMed from 1940 to 2015.
  • The search focused on retinopathy of prematurity, its history, classification, and treatment.

Main Results:

  • Clinical features, screening, and staging of ROP were detailed using the International Classification of Retinopathy of Prematurity (ICROP).
  • Current treatment indications, modalities, and outcomes from landmark randomized controlled trials were presented.

Conclusions:

  • The review aims to update pediatricians' knowledge on ROP classification and treatment.
  • Screening recommendations for ROP in India include preterm neonates <34 weeks gestation or <1750g, and those 34-36 weeks gestation or 1750-2000g with risk factors, starting by one month post-birth.
Abstract

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