Related Experiment Video
Updated: Mar 10, 2026
A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry
Published on: June 5, 2019
Bone loss & platelet-to-lymphocyte ratio
1Department of Gynecology & Obstetrics, Mugla Sitki Kocman Training & Research Hospital, Mugla, Turkey.
Aim:
The aim of the study is to assess the possible relation of platelet-to-lymphocyte ratio (PLR), neutrophil-to-platelet ratio and low-density lipoprotein cholesterol levels with low bone mineral density (BMD) in postmenopausal women.
Methodology:
In total, 211 postmenopausal women were divided into two groups according to their T-score results. The control group consisted of 32 and BMD group consisted of 179 patients. Electronic records of the patients were analyzed retrospectively.
Result(S):
PLR was statistically significantly higher in the BMD group. According to receiver operating characteristic analysis, PLR was found to be a discriminative factor for low BMD.
Conclusion:
PLR level may predict low BMD with baseline measurement in postmenopausal women.
Related Concept Videos
01:18Structure and Function of Platelets
Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000...
01:27Disorders of Leukocytes
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...