Related Experiment Video
Updated: Mar 10, 2026

Assessing the Putative Anticryptococcal Properties of Crude and Clarified Extracts from Mollusks
Published on: December 2, 2022
Bioactive phenyl ether derivatives from the marine-derived fungus Aspergillus carneus
Lan-Lan Xu1, Can-Can Zhang2, Xin-Yue Zhu1
1a Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry Education, Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Sciences , Hebei University , Baoding , China.
Abstract:
A new phenyl ether derivative, 3-hydroxy-5-(3-hydroxy-5-methylphenoxy)-4-methoxybenzoic acid (1), along with two known analogues, 3,4-dihydroxy-5-(3-hydroxy-5-methylphenoxy)benzoic acid (2) and 3-hydroxy-5-(3-hydroxy-5-methylphenoxy)benzoic acid (3), were isolated from the fungus Aspergillus carneus collected from South China Sea. The structure elucidation of 1 was determined based on extensive NMR and MS spectroscopic analyses. Compound 2 showed a strong antioxidant activity with an IC50 value of 19.3 μM which was close to the positive control ascorbic acid (IC50 = 15.3 μM).
Related Concept Videos
Fungal Phylum Ascomycota
Fungal Phylum Basidiomycota
Overview of Fungi
Fungal Group Zygomycota

