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Neuroendocrine tumour arising inside a tailgut cyst
I Mora-Guzmán1, A Alonso-Casado1, A Rodríguez Sánchez1
1Hospital Universitario de la Princesa , Madrid , Spain.
Annals of the Royal College of Surgeons of England
|December 6, 2016
Summary
Tailgut cysts, rare benign growths from embryonic hindgut remnants, can exceptionally harbor neuroendocrine tumors. This case details the surgical removal of such a cyst containing a neuroendocrine tumor.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Tailgut cysts are rare, benign retrorectal cysts originating from embryonic hindgut remnants.
- Malignant transformation within tailgut cysts is uncommon, and neuroendocrine tumors are exceedingly rare in this context.
Observation:
- A 56-year-old woman presented for surgical excision of a presacral tailgut cyst.
- The cyst was incidentally found to contain a neuroendocrine tumor during pathological examination.
Findings:
- The surgical specimen of the tailgut cyst revealed an unexpected neuroendocrine tumor.
- This represents an extremely rare occurrence of a neuroendocrine tumor within a tailgut cyst.
Implications:
- Highlights the importance of thorough pathological examination of tailgut cysts, even when presumed benign.
- Adds to the limited literature on malignant transformation and rare tumor types within tailgut cysts.
- May inform future diagnostic and management strategies for presacral lesions.

