Reconstructive surgery for treating pressure ulcers
Related Experiment Video
Updated: Mar 10, 2026

Mouse Model of Pressure Ulcers After Spinal Cord Injury
Published on: March 9, 2019
Jason Kf Wong1, Kavit Amin1, Jo C Dumville2
1Plastic and Reconstructive Surgery, University Hospital South Manchester, Southmoor Road, Wythenshawe, Manchester, UK, M23 9LT.
Background:
The management of pressure ulcers involves several interventions ranging from pressure-relieving measures such as repositioning, to treatments that can include reconstructive surgery. Such surgery may be considered for recalcitrant wounds when full thickness skin loss arises and deeper structures such as muscle fascia and even bone are exposed. The surgery commonly involves wound debridement followed by the addition of new tissue into the wound. Whilst reconstructive surgery is an accepted means of ulcer management, the benefits and harms of surgery compared with non-surgical treatments, or alternative surgical approaches are not clear.
Objectives:
To assess the effects of reconstructive surgery for healing pressure ulcers (stage II or above), comparing surgery with no surgery or comparing alternative forms of surgery in any care setting.
Search Methods:
We searched the following electronic databases to identify reports of relevant randomised clinical trials (searched 26 September 2016): the Cochrane Wounds Specialised Register, CENTRAL, MEDLINE, Embase, and CINAHL. We also searched three clinical trials registers and reference lists of relevant systematic reviews, meta-analyses and health technology assessment reports.
Selection Criteria:
Published or unpublished randomised controlled trials that assessed reconstructive surgery in the treatment of pressure ulcers.
Data Collection And Analysis:
Two review authors independently performed study selection. We planned that two review authors would also assess the risk of bias and extract study data.
Main Results:
We did not identify any studies that met the review eligibility criteria nor any registered studies investigating the role of reconstructive surgery in the management of pressure ulcers.
Authors' Conclusions:
Currently there is no randomised evidence that supports or refutes the role of reconstructive surgery in pressure ulcer management. This is a priority area and there is a need to explore this intervention with more rigorous and robust research.
More Related Videos
09:43Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair
Published on: February 24, 2016
20:33A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
Published on: July 4, 2019
Related Concept Videos
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Clinical Applications of Epidermal Stem Cells
Peripheral Artery Disease V: Postoperative Nursing Management
Phases of Wound Repair
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Peptic Ulcer Disease IV: Management
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...