Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study

Bianca Del-Ponte1, Iná S Santos1, Luciana Tovo-Rodrigues1

  • 1Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.

BMJ Open
|December 7, 2016
PubMed

Insights

Maternal caffeine intake during pregnancy was not linked to attention deficit hyperactivity disorder (ADHD) in children at age 11. This study found no association between caffeine consumption and ADHD development in offspring.

Area of Science:

  • Neuroscience
  • Epidemiology
  • Public Health

Background:

  • Limited research exists on caffeine's impact on child neurodevelopment.
  • Inconsistent findings complicate understanding of caffeine's long-term effects during pregnancy.

Purpose of the Study:

  • To investigate the association between maternal caffeine consumption during pregnancy and attention deficit hyperactivity disorder (ADHD) in children at age 11.
  • To address the scarcity of consistent evidence in this research area.

Main Methods:

  • A cohort study included all children born in Pelotas, Brazil, in 2004.
  • Maternal caffeine intake (coffee, yerba mate) was recorded at birth.
  • Childhood ADHD was assessed at age 11 using the Development and Well-Being Assessment (DAWBA) questionnaire.

Main Results:

  • The study analyzed 3485 children; ADHD prevalence was 4.1%.
  • Maternal caffeine consumption was prevalent throughout pregnancy (88.7% overall).
  • No significant association was found between maternal caffeine intake and ADHD at age 11 in crude or adjusted analyses.

Conclusions:

  • This study found no evidence linking maternal caffeine consumption during pregnancy to ADHD in offspring at age 11.
  • Further research may be needed to fully elucidate potential subtle effects or specific exposure windows.
Abstract

Related Concept Videos

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
1.2K
Stimulants01:29

Stimulants

Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
1.1K
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
505
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids01:24

CNS Stimulants: Cocaine, Amphetamines and Cannabinoids

CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its...
1.1K
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
1.2K
Information Processing Approach01:30

Information Processing Approach

The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
689