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Intestinal Bacterial Infection Diagnosed by Histological Examination of Endoscopic Biopsy Specimens

Michiko Yuki1, Yuko Emoto1, Katsuhiko Yoshizawa1

  • 1Department of Pathology II, Kansai Medical University, Hirakata, Japan.

Case Reports in Gastroenterology
|December 7, 2016
PubMed

Insights

Intestinal spirochetosis (IS) is a rare condition where spirochetal bacteria attach to the colon

Area of Science:

  • Gastroenterology
  • Microbiology
  • Histopathology

Background:

  • Intestinal spirochetosis (IS) is a colonic infection by spirochetal microorganisms.
  • IS is characterized by bacteria adhering to the colonic epithelium's surface.

Observation:

  • In a specific case, IS presented as 3-4 μm thick basophilic fringes on HE-stained biopsy specimens.
  • These fringes were identified as spirochetes using Treponema pallidum antiserum.

Findings:

  • The histological appearance of IS can be subtle, resembling thin basophilic fringes or haze.
  • These characteristic findings are crucial for accurate diagnosis, especially in regions where IS is uncommon.

Implications:

  • Recognizing the histological features of IS is vital for its diagnosis.
  • Increased awareness can prevent misdiagnosis or delayed diagnosis of this condition.
Keywords:
BacteriaBiopsyImmunohistochemistryIntestinal infection

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