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Metabolites: deciphering the molecular language between DCs and their environment.

Lucía Minarrieta1, Peyman Ghorbani1, Tim Sparwasser1

  • 1Institute of Infection Immunology, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Medical School Hannover (MHH) and the Helmholtz Centre for Infection Research (HZI), Feodor-Lynen Straße 7, 30625, Hannover, Germany.

Seminars in Immunopathology
|December 7, 2016
PubMed
Summary

Dendritic cells (DCs) interpret environmental signals beyond microbial patterns. Metabolites, from host or commensal sources, significantly influence DC function and immune responses, impacting diseases.

Keywords:
Dendritic cellsMetabolismMetabolitesMicrobiotaToleranceVitamins

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