Related Experiment Video
Updated: May 5, 2026

In Situ Detection of Autoreactive CD4 T Cells in Brain and Heart Using Major Histocompatibility Complex Class II Dextramers
Published on: August 1, 2014
Cardiac involvement by lymphoma: diagnostic difficulties.
J G Coghlan1, V E Paul, A G Mitchell
1Department of Cardiology, Harefield Hospital, Middlesex, England.
Recurrent cardiac tamponade in a patient was linked to non-Hodgkin's lymphoma. Diagnosis was complicated by tumor obstruction of the tricuspid valve and shunting via a patent foramen ovale.
Area of Science:
- Cardiology
- Oncology
- Pathology
Background:
- Cardiac lymphoma is a rare condition.
- Recurrent cardiac tamponade can be a presenting symptom.
Observation:
- A patient with recurrent tamponade was diagnosed with non-Hodgkin's lymphoma.
- Cardiac catheterization revealed tricuspid valve obstruction by tumor.
- Shunting was observed through a patent foramen ovale.
Findings:
- The study identified non-Hodgkin's lymphoma as the cause of recurrent cardiac tamponade.
- Tumor infiltration of the tricuspid valve was confirmed.
- Anatomic abnormalities like a patent foramen ovale can influence presentation.
Implications:
- This case highlights the diagnostic challenges of cardiac lymphoma.
- Early recognition of cardiac lymphoma is crucial for timely intervention.
- Understanding the interplay of cardiac tumors and intracardiac shunts is important for patient management.
More Related Videos
Related Concept Videos
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Mitral Stenosis II: Clinical features and Diagnostic Tests
Myocarditis II: Clinical Features and Diagnostic Tests
Pericarditis II: Clinical Features and Diagnostic Tests
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Cardiomyopathy IV: Restrictive Cardiomyopathy

