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Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test
Published on: November 13, 2016
[Growth curves of body weight changes in laboratory-bred female African green monkeys (Cercopithecus aethiops)]
1Corporation for Production and Research of Laboratory Primates, Ibaraki, Japan.
Abstract:
Nonlinear growth models having three or four parameter family were applied to individual weight data of female African green monkeys for estimating their growth pattern. The body weight was measured continuously from birth to six years of age with five female laboratory-bred monkeys. A total of 95 weight data were collected from each monkey. The average body weight was 330 g with the standard deviation of +/- 15 g at birth, and 2.71 +/- 0.33 kg at four years of age. The body weight of female African green monkeys was judged to reach a plateau after about four years of age. Five growth models (Gompertz, Logistic, Richards, Bertalanffy, Brody) were applied to these weight to age data. The most suitable coefficient of determination between growth data and growth model was obtained by the application of Gompertz equation. Three parameters of Gompertz equation, mature size (A), rate of maturing (K) and inflexion point (e-1 A) were analyzed in relation to age of menarche. Strong correlations between age of menarche and maturing rate, as well as between age of menarche and inflexion point were observed.

