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Total Joint Arthroplasty in Patients with Human Immunodeficiency Virus
Kalpit N Shah1, Jeremy N Truntzer2, Francine Touzard Romo1
1Department of Orthopaedic Surgery (K.N.S. and L.E.R.) and Division of Infectious Diseases, Department of Medicine (F.T.R.), Warren Alpert Medical School, Brown University, Providence, Rhode Island.
Abstract:
With the advent of highly active antiretroviral therapy (HAART), total joint arthroplasty has become a safe and effective procedure for patients infected with the human immunodeficiency virus (HIV). A correlation between a low CD4+ count (<200 cells/mm3) and major postoperative complications such as deep joint infection has been postulated, although high-level studies are not available in the literature. As most studies have not demonstrated an increase in the incidence of deep-vein thrombosis in patients with HIV/AIDS (acquired immunodeficiency syndrome), our recommendation is to use the standard prophylaxis that is followed by the operating surgeon.
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