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Evolution: Enhanced Footing for Snake Limb Development
Maria M Kaltcheva1, Mark Lewandoski1
1Cancer and Developmental Biology Laboratory, National Cancer Institute, Frederick, MD 21702, USA.
Current Biology : CB
|December 7, 2016
Abstract:
Two groups have studied the loss of limbs in snake evolution by focusing on a long-distance cis-acting enhancer of Sonic Hedgehog. They find a progressive degeneration of binding sites for key transcription factors, mirroring the progressive limblessness occurring in these reptiles.
