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The Impact of Emerging Infectious Diseases on Chinese Blood Safety
Miao He1, Jingxing Wang1, Limin Chen1
1Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Chengdu, Sichuan, China.
Insights
Emerging infectious diseases (EIDs) pose a significant threat to blood safety in China. This review examines 9 EID agents, their epidemiology, and risks to transfusion safety, proposing strategies to enhance hemovigilance.
Area of Science:
- Public Health
- Infectious Diseases
- Transfusion Medicine
Background:
- Emerging infectious diseases (EIDs) represent a persistent global public health challenge.
- Mandatory screening for HIV, HBV, HCV, and syphilis has improved blood safety but EID threats remain.
- The impact of EIDs on China's blood supply is not fully characterized.
Purpose of the Study:
- To review the epidemiologic status and distribution of 9 key EID agents in China.
- To assess the potential risks these EID agents pose to blood safety.
- To explore strategies for strengthening hemovigilance and evaluating EID impact.
Main Methods:
- Literature review of autochthonous and epidemic EID agents in China.
- Summary of epidemiologic data in donor and healthy populations.
- Discussion of transfusion-related risks and hemovigilance strategies.
Main Results:
- Identified 9 representative EID agents prevalent nationally or regionally in China.
- Summarized current epidemiologic status and distribution of these agents.
- Highlighted the potential risks of EIDs to blood safety in the Chinese context.
Conclusions:
- EIDs present ongoing risks to blood safety in China beyond classical transfusion-transmitted infections.
- Strengthening hemovigilance systems is crucial for mitigating these risks.
- Further research is needed to fully understand and manage the impact of EIDs on blood safety.
Abstract:
Emerging infectious diseases (EIDs) have always been one of the major threats to public health. Although the implementation of mandatory testing for 4 classical transfusion-transmitted infectious-human immunodeficiency virus, hepatitis B virus, hepatitis C virus, and syphilis-has reduced the transfusion risk of these pathogens, the potential threat of various EID agents and their constantly evolving variants to blood safety in China is not fully understood. This review presents 9 representative EID agents that are autochthonous and epidemic nationally or regionally in China. The epidemiologic status and distribution of these EID agents among donors and/or healthy populations are summarized. The potential risks of these EID agents to blood safety are discussed. The review also explores strategies to strengthen hemovigilance systems and studies to further evaluate the impact of EID agents on blood safety.
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