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Updated: Jul 28, 2026
07:58
Non-Terminal Blood Sampling Techniques in Guinea Pigs
Published on: October 11, 2014
[Benzonal metabolism in guinea pigs]
Farmakologiia I Toksikologiia
|May 1, 1989
Abstract:
A metabolite of an anticonvulsant drug Benzonal was isolated from the guinea pig blood serum and identified by high performance liquid chromatography (HPLC). By using HPLC as well as ultraviolet-, infrared- and mass-spectrometry it was established that in the guinea pig intestine Benzonal undergoes alkaline hydrolysis with the formation of phenobarbital. The native Benzonal in the guinea pig blood serum was not found.
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