Related Experiment Video
Updated: Mar 10, 2026

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging
Published on: March 13, 2019
Operating principles of rotary molecular motors: differences between F1 and V1 motors
Ichiro Yamato1, Yoshimi Kakinuma2, Takeshi Murata3
1Department of Biological Science and Technology, Tokyo University of Science, Tokyo 125-8585, Japan.
Abstract:
Among the many types of bioenergy-transducing machineries, F- and V-ATPases are unique bio- and nano-molecular rotary motors. The rotational catalysis of F1-ATPase has been investigated in detail, and molecular mechanisms have been proposed based on the crystal structures of the complex and on extensive single-molecule rotational observations. Recently, we obtained crystal structures of bacterial V1-ATPase (A3B3 and A3B3DF complexes) in the presence and absence of nucleotides. Based on these new structures, we present a novel model for the rotational catalysis mechanism of V1-ATPase, which is different from that of F1-ATPases.
Related Concept Videos
Relative Motion Analysis - Velocity
When an external force is exerted, it sets the crank into a rotational movement. This, in turn, instigates the motion of the connecting rod, leading to what is referred to as a general plane motion. This process involves two key points - point A on the connecting rod...
ATP Driven Pumps III: V-type Pumps
The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...
Electro-mechanical Systems
A key component of the DC motor is the armature, a rotating circuit positioned within a magnetic field. As an electric current passes through the...
Motor Units
Motor units come in different sizes, with smaller units...
Motor Units
Force On A Current Loop In A Magnetic Field

