[Lipoprotein cholesterol in the blood plasma of rats with a bile circulation disorder]

The experiments were carried out on two groups of rats with obstruction or cannulation of bile duct. Plasma was obtained from the tail venous blood before and 24 hours after operation. The bile duct obstruction caused hypercholesterolemia and considerable increase in the cholesterol content of low-density and very low-density lipoprotein (cholesterol bound to LDL and VLDL). Cannulation of total bile duct slightly increased CH-LDL+VLDL. The change in concentration of high-density lipoprotein cholesterol was insignificant in both models of bile disturbance while index of atherogenesis increased.