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Published on: August 2, 2017
Postnatal outcome and placental blood flow after plasmapheresis during pregnancy
Mária Jakó1, Andrea Surányi1, Márta Janáky2
1a Department of Obstetrics and Gynecology , University of Szeged , Szeged , Hungary.
Purpose:
Plasmapheresis in pregnancy adversely affects maternal hemodynamics, however there are studies suggesting it to reduce pregnancy loss in immunological diseases when medication is more harmful to the fetus. The overall optimal plasmapheresis treatment protocol remains unknown.
Materials And Methods:
A pregnant with neuromyelitis optica was followed up after receiving six volumes of fresh frozen plasma via plasmapheresis.
Results:
The placenta compensated the hemodynamic change until the 33rd week of gestation, resulting a small for gestational age, otherwise healthy girl.
Conclusions:
More research is needed on plasma exchange during pregnancy because in our observation placental circulation can adapt to the change in blood pressure.

