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Updated: Mar 10, 2026
Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Published on: June 29, 2013
Myocardial dysfunction in children with intrauterine growth restriction: an echocardiographic study
Katarzyna Niewiadomska-Jarosik1, Justyna Zamojska1, Agata Zamecznik1
1Department of Pediatric Cardiology and Rheumatology, 2nd Chair of Pediatrics, Medical University of Lodz, Poland.
Introduction:
The prevalence of intrauterine growth restriction (IUGR) is about 3-10% of live-born newborns and can be as high as 20% in developing countries. It may result in the occurrence of cardiovascular diseases later in life.
Methods:
The aim of this study was echocardiographic evaluation, with the use of conventional and tissue Doppler parameters, of cardiac function in children born with IUGR, and comparison with healthy peers born as normally grown foetuses.
Results:
In the IUGR group, E wave and E/A ratio were significantly lower compared to the control group. A wave, isovolumetric relaxation time, deceleration time, myocardial performance index as well as E/E' septal and E/E' lateral indices were significantly higher compared to healthy peers.
Conclusion:
Children with IUGR presented with subclinical myocardial dysfunction.
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