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Risk Factors for Perimegaprosthetic Infections After Tumor Resection
Abstract:
Periprosthetic joint infection remains one of the most challenging and pervasive complications following megaprosthetic replacement after tumor resection. The authors conducted a systematic review of the literature for clinical studies that reported a risk factor analysis for perimegaprosthetic joint infections. The search included English-language studies published up to July 2015. Eight studies fulfilled the inclusion criteria. Identified factors mostly related to both surgical procedure and hospitalization. Physicians should consider these results when discussing the outcomes of limb salvage surgery with patients and trying to reduce the overall burden of perimegaprosthetic joint infections. [Orthopedics. 2017; 40(1):e11-e16.].
Insights
Periprosthetic joint infections are a major risk after tumor resection megaprosthetic replacement. Factors influencing these infections are linked to the surgical procedure and hospitalization, requiring careful consideration by physicians.
Area of Science:
- Orthopedics
- Oncology
- Infectious Diseases
Background:
- Periprosthetic joint infection (PJI) is a significant complication after megaprosthetic replacement in tumor resection.
- Managing PJI presents substantial challenges in orthopedic oncology.
Purpose of the Study:
- To systematically review and identify risk factors associated with perimegaprosthetic joint infections following tumor resection megaprosthetic replacement.
Main Methods:
- A systematic literature review was conducted, including English-language studies published up to July 2015.
- Eight studies met the inclusion criteria for risk factor analysis.
Main Results:
- Identified risk factors for perimegaprosthetic joint infections were predominantly associated with the surgical procedure.
- Hospitalization-related factors also emerged as significant contributors to infection risk.
Conclusions:
- Physicians should integrate these findings into patient discussions regarding limb salvage surgery outcomes.
- Understanding these risk factors is crucial for reducing the incidence and burden of perimegaprosthetic joint infections.
