Related Experiment Video
Updated: Mar 10, 2026

Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay
Published on: April 28, 2022
Control of scarring: critique II
1Professor of surgery, University of Newcastle, North Tees Hospital, Stockton-on-Tees.
Abstract:
It Is now widely known that wounds Inflicted in utero on the fetus of some mammalian species can heal without scarring. This has potential in the management of wounds in adults, the result being that there could be complete restoration of tissue integrity with no cosmetic disfigurement. The normal response to trauma Involves a complicated acute inflammatory response mediated mainly through the macrophage and cytokine cascades. This has become established through our evolution and it is not known what may result from interference using genetically engineered manipulations or addition of factors which promote or inhibit stages of the inflammatory response.
Related Concept Videos
Clinical Applications of Epidermal Stem Cells
Overview of Regeneration and Repair
Regeneration
All animals have varying degrees of...
Phases of Wound Repair
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...

