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Published on: December 11, 2017
Survival and quality of life after aortic coarctation repair
Inês Santos Silva1, Jorge Casanova
1Departamento de Cirurgia Cardiotorácica do Hospital de S. João e Faculdade de Medicina da Universidade do Porto, Portugal.
Insights
Surgical repair of aortic coarctation is safe, but long-term risks like hypertension and re-coarctation persist. Despite this, patients report a quality of life comparable to the healthy population.
Area of Science:
- Cardiology
- Pediatric Surgery
- Congenital Heart Disease
Background:
- Coarctation of the aorta is a common congenital heart defect requiring surgical intervention.
- While survival rates are high, long-term morbidity and mortality remain concerns, especially with associated cardiac lesions.
- Understanding the long-term impact on quality of life is crucial for patient management.
Purpose of the Study:
- To evaluate surgical outcomes, long-term survival, and quality of life in patients undergoing aortic coarctation repair.
- To identify factors influencing survival and complications post-surgery.
- To assess the health-related quality of life in adult survivors.
Main Methods:
- Retrospective analysis of patients under 1 year old treated between 1998-2005.
- Surgical results, survival data, and complication rates were reviewed.
- A patient survey assessed current quality of life.
Main Results:
- Fifty patients were studied; 40% were neonates, and 62% required urgent repair.
- Resection and end-to-end anastomosis was the most common technique (64%).
- Actuarial survival reached 88% at 17 years; complex coarctation correlated with lower survival (p=0.007). Patients reported quality of life similar to healthy individuals.
Conclusions:
- Surgical repair of aortic coarctation is generally safe with good long-term survival.
- Patients face risks of hypertension, re-coarctation, and late mortality.
- Despite potential complications, patients report a quality of life comparable to the general population.
Introduction:
Coarctation of the aorta is the fifth most common congenital heart disease in clinical practice. Surgical repair has been performed in infants with high survival; still patients maintain a high risk of morbidity and mortality, moreover in the presence of associated cardiac lesions. Thus, it is imperative a medical follow-up of these patients in order to understand the impact of the disease in their quality of life.
Objectives:
To report the surgical results, long term survival, complications and present health related quality of life of patients submitted to surgical repair of aortic coarctation.
Methods:
Retrospective review of all patients younger than 1 year old submitted to surgery, between 1998 and 2005, at Centro Hospitalar São João. A survey was answered by the patients to address present quality of life.
Results:
Fifty patients were available for study. Twenty patients (40,0%) were neonates at the time of surgery and 31 (62%) presented to urgent repair. Isolated coarctation was noticed in 25 patients (50,0%) and the most common surgical technique was resection and end-to-end anastomosis, in 64,0%. Early mortality was 4,0% and zero in patients with isolated coarctation. Actuarial survival rates were 90,0%, 88,0% and 88,0% at 5, 10 and 17 years of follow-up, respectively. Complex coarctation was associated with decreased survival (p = 0,007). Patients reported in questionnaires similar results to healthy population.
Conclusion:
Surgical repair of aortic coarctation is a relatively safe surgery, however patients maintain risks of arterial hypertension, re-coarctation and mortality at long term. Nevertheless, patients report a quality of life that is no different than healthy population.
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