Survival and quality of life after aortic coarctation repair

Inês Santos Silva1, Jorge Casanova

  • 1Departamento de Cirurgia Cardiotorácica do Hospital de S. João e Faculdade de Medicina da Universidade do Porto, Portugal.

Insights

Surgical repair of aortic coarctation is safe, but long-term risks like hypertension and re-coarctation persist. Despite this, patients report a quality of life comparable to the healthy population.

Area of Science:

  • Cardiology
  • Pediatric Surgery
  • Congenital Heart Disease

Background:

  • Coarctation of the aorta is a common congenital heart defect requiring surgical intervention.
  • While survival rates are high, long-term morbidity and mortality remain concerns, especially with associated cardiac lesions.
  • Understanding the long-term impact on quality of life is crucial for patient management.

Purpose of the Study:

  • To evaluate surgical outcomes, long-term survival, and quality of life in patients undergoing aortic coarctation repair.
  • To identify factors influencing survival and complications post-surgery.
  • To assess the health-related quality of life in adult survivors.

Main Methods:

  • Retrospective analysis of patients under 1 year old treated between 1998-2005.
  • Surgical results, survival data, and complication rates were reviewed.
  • A patient survey assessed current quality of life.

Main Results:

  • Fifty patients were studied; 40% were neonates, and 62% required urgent repair.
  • Resection and end-to-end anastomosis was the most common technique (64%).
  • Actuarial survival reached 88% at 17 years; complex coarctation correlated with lower survival (p=0.007). Patients reported quality of life similar to healthy individuals.

Conclusions:

  • Surgical repair of aortic coarctation is generally safe with good long-term survival.
  • Patients face risks of hypertension, re-coarctation, and late mortality.
  • Despite potential complications, patients report a quality of life comparable to the general population.
Abstract

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