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Updated: Mar 10, 2026
Translational Orthotopic Models of Glioblastoma Multiforme
Published on: February 17, 2023
Primary pineal glioblastoma multiforme mimicking a germ cell tumour
Syed Sameer Nadvi1,2, Kritish Timatkia1
1a Department of Neurosurgery, Nelson R Mandela School of Medicine , University of KwaZulu-Natal , Durban , South Africa.
Abstract:
Glioblastoma multiforme (GBM) is extremely rare in the pineal region, with only 19 previously reported cases. We report a unique case of a teenage girl with a pineal tumour with markedly raised beta-human chorionic gonadotropin (BHCG) levels, thought to be a germ-cell tumour. However, the raised BHCG was due to pregnancy, and biopsy revealed a pineal GBM.
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