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Long-Term Clinical Outcomes and Prognostic Factors After Pericardiectomy for Constrictive Pericarditis in a Japanese

Shunsuke Nishimura1, Chisato Izumi, Masashi Amano

  • 1Department of Cardiology, Tenri Hospital.

Circulation Journal : Official Journal of the Japanese Circulation Society
|December 9, 2016
PubMed

Insights

Long-term outcomes after pericardiectomy for constrictive pericarditis (CP) depend on etiology and patient condition. Postoperative cardiac catheterization can predict prognosis, guiding treatment for heart failure.

Area of Science:

  • Cardiology
  • Cardiac Surgery

Background:

  • Constrictive pericarditis (CP) impairs diastolic function, leading to heart failure.
  • Pericardiectomy is a treatment for CP, but long-term outcome data are limited.

Purpose of the Study:

  • To investigate long-term clinical outcomes after pericardiectomy for CP.
  • To identify predictors of cardiac events and assess the role of etiology.

Main Methods:

  • Retrospective analysis of 45 patients undergoing pericardiectomy for CP.
  • Examined preoperative factors, cardiac catheterization parameters, and cardiac events (heart failure hospitalization or cardiac death).
  • Median follow-up was 5.7 years.

Main Results:

  • 5-year event-free survival was 65%.
  • Idiopathic and tuberculosis-related CP had better outcomes than post-cardiac surgery CP.
  • Predictors of adverse events included higher age, atrial fibrillation, advanced NYHA class, and elevated pulmonary artery pressure.

Conclusions:

  • Long-term outcomes are influenced by CP etiology and preoperative patient status.
  • Postoperative cardiac catheterization findings, particularly right-atrial pressure, may predict prognosis.
Abstract

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