[Blood coagulation changes in lung surgery and their prevention by heparin]

Changes of hemocoagulation were studied in three groups of patients in different periods of surgical intervention for various forms of pulmonary tuberculosis. Mini-doses of heparin were included in the complex of preventive measures applied during the operation in group 3. It was found out that changes of blood coagulation during operation on phthisiosurgical patients develop according to the mechanism of the thrombohemorrhagic syndrome (THS). The more injurious the operation, the more manifest are the changes in the system of blood coagulation and fibrinolysis. Heparin prevents intravascular coagulation of blood, arrest the development of THS and, in this manner, the occurrence of thrombohemorrhagic complications.