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Updated: Mar 10, 2026

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation
Published on: September 4, 2017
Validation of an improved helical diode array and dose reconstruction software using TG-244 datasets and stringent
Saeed Ahmed1, Benjamin Nelms, Jakub Kozelka
1University of South Florida. saeed.ahmed@moffitt.org.
A software update for the ArcCHECK (AC) diode array corrects for design changes, ensuring accurate 3D dose reconstruction for radiation therapy. This ensures reliable measurements despite updated diode responses to scattered radiation.
Area of Science:
- Medical Physics
- Radiation Oncology
- Dosimetry
Background:
- The helical ArcCHECK (AC) diode array is crucial for 3D dose reconstruction in radiation therapy.
- Recent design modifications to the AC reduced diode overresponse to scattered radiation, improving accuracy but impacting existing dose reconstruction models.
- This necessitated a re-evaluation and adaptation of the measurement and reconstruction processes.
Purpose of the Study:
- To characterize and validate the updated ArcCHECK (AC) diode array and its associated 3D dose reconstruction software (3DVH).
- To introduce and assess a software correction mechanism to account for design changes in the AC without altering model parameters.
- To ensure continued accuracy in radiation dose measurements and reconstruction following AC hardware revisions.
Main Methods:
- A correction factor was implemented in the 3DVH software to compensate for differences in out-of-field response between new and old AC designs.
- The optimal correction factor was determined by minimizing dose differences using an ionization chamber.
- Verification utilized AAPM TG-244 standard cases and comparisons with ionization chambers and a Delta4 diode array using gamma analysis.
Main Results:
- A single correction factor of 1.17 provided satisfactory results across multiple radiation energies (6X, 15X, 10XFFF).
- Reconstructed dose in targets showed minimal difference (0.0% ± 1.4%) compared to ionization chamber measurements in a water-equivalent phantom.
- Gamma analysis with a Delta4 system demonstrated high agreement rates (96.7% ± 3.7% overall, 98.3% ± 0.8% for common plans).
Conclusions:
- The implemented software correction mechanism effectively addresses the dosimeter response changes due to AC design modifications.
- The updated system maintains high accuracy for 3D measurement-guided dose reconstruction.
- This ensures the reliability of the ArcCHECK system for clinical applications following hardware revisions.
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