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Related Experiment Videos

[Tonic pupil caused by ischemia].

H Wilhelm

    Fortschritte Der Ophthalmologie : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
    |January 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Tonic pupils, often idiopathic, can be linked to giant cell arteritis and ischemic events. This study highlights their potential association with various vascular conditions impacting the eye.

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    Area of Science:

    • Ophthalmology
    • Neurology
    • Vascular Medicine

    Background:

    • Tonic pupils are typically idiopathic, resulting from ciliary ganglion lesions.
    • Ischemia rarely causes ciliary ganglion lesions due to its robust blood supply.

    Observation:

    • This study presents five cases of tonic pupils associated with giant cell arteritis.
    • Associated findings included ischemic optic neuropathy and supratrochlear artery blood flow stagnation.
    • Tonic pupils were also observed following internal carotid artery occlusion resolution and in cases of choroidal ischemia.

    Findings:

    • Tonic pupils may be more common in giant cell arteritis than previously reported.
    • Vascular occlusive events and inflammatory conditions can lead to tonic pupils.
    • Pharmacological testing with 0.1% pilocarpine confirmed tonic pupil diagnosis via cholinergic hypersensitivity.

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    Implications:

    • Giant cell arteritis should be considered in the differential diagnosis of tonic pupils.
    • Understanding the vascular underpinnings of tonic pupils can improve diagnostic approaches.
    • Further research is warranted to explore the prevalence and mechanisms of tonic pupils in vascular diseases.