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Hyperthyroidism secondary to hysterosalpingography: an extremely rare complication: A case report
Guotao Ma1, Rui Mao, Haixin Zhai
1Department of Cardiac Surgery, Peking Union Medical College Hospital, Beijing, China Department of Plastic Surgery, Plastic Surgery Hospital (Institute), Chinese Academy of Medical Science & Peking Union Medical College (CAMS & PUMC), Beijing, China.
Medicine
|December 9, 2016
Summary
Hysterosalpingography (HSG) can cause iodine-induced hyperthyroidism (IIH) in euthyroid patients. This case highlights HSG as a potential trigger for IIH, emphasizing excessive iodine absorption.
Area of Science:
- Endocrinology
- Radiology
Background:
- Hysterosalpingography (HSG) is a standard infertility diagnostic tool.
- Known HSG complications include uterine perforation, infection, and allergic reactions.
- Hyperthyroidism is a previously unreported complication of HSG.
Observation:
- A 33-year-old euthyroid woman developed hyperthyroid symptoms post-HSG.
- Thyroid function tests revealed suppressed TSH, elevated free T4 and T3, and high serum and urinary iodine levels.
- The patient presented with palpitations, hand tremor, fatigue, and sweating.
Findings:
- The patient was diagnosed with iodine-induced hyperthyroidism (IIH).
- No antithyroid drug treatment was administered.
- The patient experienced spontaneous recovery and is currently pregnant.
Implications:
- This is the first reported case of overt IIH following HSG in an at-risk euthyroid patient.
- HSG may lead to significant iodine absorption, potentially inducing secondary hyperthyroidism.
- Clinicians should consider IIH in patients presenting with hyperthyroid symptoms after HSG.
