Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Atrophic, autoimmune thyroiditis in infancy. A case report.

G Z Ostergaard1, B B Jacobsen

  • 1Department of Paediatrics, Roskilde Hospital, Denmark.

Hormone Research
|January 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cardiotoxicity of environmental contaminant tributyltin involves myocyte oxidative stress and abnormal Ca<sup>2+</sup> handling.

Environmental pollution (Barking, Essex : 1987)·2019
Same author

Hyperinsulinemic hypoglycemia in Beckwith-Wiedemann syndrome due to defects in the function of pancreatic beta-cell adenosine triphosphate-sensitive potassium channels.

The Journal of clinical endocrinology and metabolism·2005
Same author

Cushing's disease in childhood as the first manifestation of multiple endocrine neoplasia syndrome type 1.

European journal of endocrinology·2004
Same author

Association of a putative regulatory polymorphism in the PD-1 gene with susceptibility to type 1 diabetes.

Tissue antigens·2003
Same author

Late relapse of adrenocortical carcinoma in Beckwith-Wiedemann syndrome. Clinical, endocrinological and genetic aspects.

Acta paediatrica (Oslo, Norway : 1992)·2003
Same author

A prospective study of thyroid function, morphology and autoimmunity in young patients with type 1 diabetes.

European journal of endocrinology·2003
Same journal

Abstracts of the LWPES/ESPE 8th Joint Meeting Global Care in Paediatric Endocrinology, in collaboration with APEG, APPES, JSPE and SLEP. New York City, New York, USA. September 9-12, 2009.

Hormone research·2011
Same journal

Abstracts of the 47th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE). Istanbul, Turkey. September 20-23, 2008.

Hormone research·2011
Same journal

Abstracts of the 46th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE). Helsinki, Finland. June 27-30, 2007.

Hormone research·2011
Same journal

Genetic and pathogenetic aspects of Noonan syndrome and related disorders.

Hormone research·2009
Same journal

Response to growth hormone in short children with Noonan syndrome: correlation to genotype.

Hormone research·2009
Same journal

Growth hormone and the heart in Noonan syndrome.

Hormone research·2009
See all related articles

Autoimmune thyroiditis in infancy is extremely rare, with only two cases reported. This study details a fatal case of acquired primary hypothyroidism in a 7-month-old, highlighting the condition's severity in infants.

Area of Science:

  • Pediatric Endocrinology
  • Immunology
  • Pathology

Background:

  • Autoimmune thyroiditis is uncommon in infants, with limited prior case reports.
  • Acquired primary hypothyroidism presents a diagnostic challenge in early childhood.

Observation:

  • A 7-month-old infant presented with acquired primary hypothyroidism and high thyroid microsomal antibody titers.
  • The infant developed a sepsis-like condition and died at 9 months of age.
  • Autopsy confirmed atrophic thyroiditis.

Findings:

  • This case represents the second reported instance of autoimmune thyroiditis in infancy.
  • The infant's clinical presentation was severe and complex, consistent with aggressive autoimmune disease.
  • Post-mortem examination revealed significant thyroid atrophy.

Related Experiment Videos

Implications:

  • Autoimmune thyroiditis in infancy may present with a more severe clinical course than in older children.
  • Understanding these severe presentations is crucial for early diagnosis and management.
  • Further research is needed to elucidate the pathogenesis and long-term outcomes of infantile autoimmune thyroiditis.