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Published on: May 26, 2023
Percutaneous transvenous mitral commissurotomy in mitral stenosis and left atrial appendage clot patients in special
Rajib Rajbhandari1, Rabi Malla1, Arun Maskey1
1Shahid Gangalal National Heart Centre, Kathmandu, Nepal.
Insights
Percutaneous transvenous mitral commissurotomy is safe for mitral stenosis patients with left atrial appendage clot in urgent situations. This procedure offers an acceptable solution, improving outcomes without immediate complications.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Mitral stenosis is a condition often treated with percutaneous transvenous mitral commissurotomy (PTMC).
- Left atrial appendage (LAA) clot is a common complication that prevents patients from undergoing PTMC.
- Urgent intervention is sometimes necessary for patients with mitral stenosis and LAA clot who cannot receive anticoagulation.
Purpose of the Study:
- To evaluate the feasibility and safety of PTMC in patients with mitral stenosis and LAA clot requiring urgent intervention.
- To assess the procedural success and immediate outcomes in this specific patient cohort.
Main Methods:
- Twenty patients with mitral stenosis (mitral valve area <1.5cm²), significant dyspnea, LAA clot, and urgent intervention needs were selected.
- The study was conducted between January 2011 and December 2013 at Shahid Gangalal National Heart Centre, Kathmandu.
- Informed consent and ethical approval were obtained prior to the procedure.
Main Results:
- PTMC successfully increased the mean mitral valve area from 0.90cm² to 1.5cm² (p=0.02).
- Mean left atrial pressure decreased from 20mmHg to 10mmHg, with subjective improvement reported in all patients.
- No mortality, neurological complications, or need for emergency surgery occurred during the hospital stay or one-week follow-up.
Conclusions:
- PTMC is a safe and feasible procedure for selected mitral stenosis patients with LAA clot in urgent situations.
- The procedure yields acceptable immediate results when performed by experienced clinicians.
- This approach provides a viable treatment option for patients who cannot undergo standard anticoagulation therapy.
Background:
The percutaneous transvenous mitral commissurotomy is an important procedure for the treatment of mitral stenosis. A lot of mitral stenosis cases have left atrial appendage clot which precludes the patient from the benefit of this procedure. The aim of the study was to study the feasibility and safety of the procedure in a patient with appendage clot in the setup of certain urgent conditions.
Method:
All cases of mitral stenosis with significant dyspnea and mitral valve area <1.5cm2 with left atrial appendage clot and a condition which would preclude the patient from continuing on anticoagulation and needed urgent intervention were included in the study. From January 2011 to December 2013, twenty patients coming to Shahid Gangalal National Heart Centre, Kathmandu were selected for the procedure with conventional sampling technique. Informed written consent was obtained from the patients explaining all possible complications. The approval of the study was taken from the ethical committee of the hospital.
Result:
Mean mitral valve area increased from 0.90cm2 (SD±0.14) to 1.5cm2 (SD±0.21) (p=0.02). Left atrial mean pressure decreased from mean of 20 to 10mmHg. Subjective improvement was reported in all. All of the patients had fulfilled criteria for successful PTMC. There was no mortality during hospital stay or in one-week follow-up period. There were no neurological complications or any need for emergency surgery.
Conclusion:
The immediate result of percutaneous transvenous mitral commissurotomy in selected cases of mitral stenosis with left atrial appendage clot is safe and acceptable in certain urgent situations in experienced hands.
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