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Risk factor profile of calcific aortic stenosis
I Sathyamurthy1, Shaji Alex2, K Kirubakaran3
1Department of Cardiology, Apollo Main Hospital, Chennai, India.
Indian Heart Journal
|December 10, 2016
Summary
Calcific aortic stenosis (CAS) patients with coronary artery disease (CAD) have a higher prevalence of diabetes, hypertension, dyslipidemia, smoking, and family history. Diabetes was the only statistically significant difference observed between groups.
Area of Science:
- Cardiology
- Vascular Medicine
- Public Health
Background:
- Calcific aortic stenosis (CAS) and coronary artery disease (CAD) share common risk factors.
- Previous studies on statin use for CAS progression yielded inconsistent results.
Purpose of the Study:
- To compare the prevalence of cardiovascular risk factors in patients with calcific aortic stenosis (CAS) with and without associated coronary artery disease (CAD).
Main Methods:
- 110 patients over 40 with CAS underwent clinical, biochemical, and echocardiographic evaluation.
- Coronary angiograms were performed in 66% of patients.
Main Results:
- Patients with CAS and CAD exhibited higher rates of diabetes (65% vs. 30%), hypertension (52% vs. 43%), dyslipidemia (69% vs. 52%), smoking (24% vs. 18%), and family history of CAD (34% vs. 16%).
- Obesity was more prevalent in patients without CAD (30% vs. 20%).
Conclusions:
- Diabetes mellitus was the only risk factor with a statistically significant difference between CAS patients with and without CAD.
- Findings highlight the significant overlap in risk factors between CAS and CAD, emphasizing the need for comprehensive cardiovascular risk management.
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