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Multifidus Degeneration, A New Risk Factor for Lumbar Spinal Stenosis: A Case-Control Study
Jiayao Jiang1, Haibin Wang1, Liang Wang1
1Department of Orthopaedics, Changzheng Hospital Affiliated to the Second Military Medical University, Shanghai, China.
World Neurosurgery
|December 10, 2016
Summary
Multifidus degeneration is linked to lumbar spinal stenosis (LSS). Degenerate multifidus muscles show reduced volume, increased fat, and asymmetry in LSS patients compared to healthy individuals.
Area of Science:
- Orthopedics
- Radiology
- Spinal Surgery
Background:
- Degenerative lumbar spinal stenosis (LSS) is a common condition.
- The multifidus muscle plays a crucial role in spinal stability.
- Understanding multifidus degeneration in LSS is important for treatment.
Purpose of the Study:
- To investigate the relationship between multifidus degeneration and degenerative lumbar spinal stenosis (LSS).
Main Methods:
- Retrospective analysis of 40 LSS patients and 40 healthy controls.
- 1.5-T lumbar spinal MRI scans were performed for all subjects.
- Multifidus muscularity, fatty infiltration, and asymmetry at L4/5 were quantified using ImageJ software.
Main Results:
- LSS patients exhibited significantly lower multifidus muscularity compared to controls.
- Patients with LSS showed a greater fatty infiltration ratio in the multifidus muscle.
- Increased bilateral muscle asymmetry of the multifidus was observed in the LSS group.
Conclusions:
- Multifidus degeneration, characterized by reduced volume, increased fatty infiltration, and asymmetry, is associated with degenerative lumbar spinal stenosis.
- These findings highlight the role of multifidus muscle changes in the pathophysiology of LSS.
- Further research may explore therapeutic interventions targeting multifidus degeneration in LSS management.

