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Related Experiment Videos

Metformin associated lactic acidosis.

P J Phillips, R Scicchitano, A R Clarkson

    Australian and New Zealand Journal of Medicine
    |June 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Metformin can cause lactic acidosis, especially with excessive use or in patients with kidney, heart, or liver issues. This risk, though lower than with phenformin, necessitates careful patient selection for metformin therapy.

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    Area of Science:

    • Pharmacology
    • Clinical Medicine
    • Toxicology

    Background:

    • Metformin is a widely used antidiabetic drug.
    • Lactic acidosis is a rare but serious complication associated with metformin.
    • Previous reports indicate a link between metformin and lactic acidosis, particularly in patients with underlying health conditions.