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Overview of Exosomes01:36

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Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
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Exocytosis is a process that releases molecules outside the cell. Like other bulk transport mechanisms, exocytosis requires energy.
Exocytosis is the opposite of endocytosis, which brings molecules inside the cell. Sometimes, the released materials are signaling molecules. For example, neurons typically use exocytosis to release neurotransmitters. Cells also use exocytosis to insert proteins such as ion channels into their cell membranes, secrete proteins for use in the extracellular matrix, or...
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Vesicular transport is a cellular process that encompasses the engulfment of particles or dissolved substances by cells. It involves endocytosis, transcytosis, and exocytosis.
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Isolation and Characterization of Exosomes from Skeletal Muscle Fibroblasts
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Exosomes: What Do We Love So Much About Them?

Michael E Davis1

  • 1From the Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta; Division of Cardiology, Emory University School of Medicine, Atlanta, GA; and Children's Heart Research and Outcomes Center, Emory University School of Medicine and Children's Healthcare of Atlanta, GA. michael.davis@bme.emory.edu.

Circulation Research
|December 10, 2016
PubMed
Summary

No abstract available in PubMed .

Keywords:
biomarkerscardiovascular systemexosomemicroRNAsystems biology

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