[Influencial factors for in-hospital patients with ST segment elevation myocardial infarction after emergency
Chenyang Chen1, Yiyuan Huang1, Shenghua Zhou1
1Department of Cardiovascular Medicine, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Insights
Emergency percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) shows a 22% adverse event rate. Key predictors for in-hospital cardiac events include hematocrit, NT-proBNP, Killip grade, TIMI flow, ST-segment resolution, and door-to-balloon time.
Area of Science:
- Cardiology
- Interventional Cardiology
- Acute Myocardial Infarction Management
Background:
- Acute myocardial infarction (AMI) requires timely intervention.
- Emergency percutaneous coronary intervention (PCI) is a critical treatment for ST-segment elevation myocardial infarction (STEMI).
- Identifying prognostic factors is crucial for improving patient outcomes.
Purpose of the Study:
- To analyze clinical outcomes of emergency PCI in AMI patients.
- To identify risk factors predicting prognosis and in-hospital cardiac events.
Main Methods:
- Retrospective analysis of 304 STEMI patients undergoing emergency PCI (2010-2014).
- Patients categorized based on cardiovascular event occurrence.
- Comparison of clinical factors between groups using t-tests and chi-squared analysis.
- Logistic regression to identify predictors of in-hospital cardiac events.
Main Results:
- The incidence of adverse events was 22% (67/304).
- Statistically significant differences were observed in hematocrit (HCT), NT-proBNP, White Blood Cell count (WBC), age, Killip grade, TIMI flow post-PCI, arrhythmia, multi-vessel disease, ST-segment resolution, and door-to-balloon (D2B) time.
- Logistic analysis identified HCT, NT-proBNP, Killip grade ≥2, TIMI flow ≤2, ST-segment resolution ≥50%, and long D2B time as significant predictors of in-hospital cardiac events.
Conclusions:
- Hematocrit, NT-proBNP levels, Killip grade, post-PCI TIMI flow, ST-segment resolution, and D2B time are key predictors of in-hospital cardiac events in AMI patients undergoing emergency PCI.
- Addressing these high-risk factors can potentially improve prognosis and reduce adverse events.
Objective:
To analyze the clinical outcomes of emergency percutaneous intervention in acute myocardial infarction (AMI) during hospital, and to find the relevant risk factors for the prognosis and cardiac events. Methods: We retrospective analyzed the patient with acute ST segment elevation myocardial infarction, who was successfully performed emergency percutaneous coronary intervention (PCI) in the Cardiac Cath Lab of the Second Xiangya Hospital from January 2010 to December 2014. According to situation for cardiovascular events, patients were divided into 2 groups. The clinical factors were compared between the 2 groups. Results: The incidence of adverse event was 22% (67/304). By using t test and χ2 analysis, we found that Cr, NT-proBNP, HCT, WBC, age>75, Killip grade≥2, TIMI flow after PCI≤2, arrhythmia, multi-vessel lesion, ST-segment resolution≥50%, long D2B time are statistically different between the 2 groups. Logistic analysis revealed that HCT, NT-proBNP, Killip grade≥2, TIMI flow after PCI≤2, ST-segment resolution≥50%, long D2B time were important predictors for cardiac events in-hospital. Conclusion: HCT, NT-proBNP, Killip grade≥2, TIMI flow after PCI≤2, ST-segment resolution≥50%, long D2B time are important predictors for cardiac events in-hospital. The prognosis for AMI patient after emergency PCI could be improved and the incidence of cardiac event in hospital could be reduced if the high risk factors can be properly handled.
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