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Updated: Mar 10, 2026
A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
Published on: August 8, 2020
[Application of combination of xenoskin with delayed microskin graft in extensively burned patients]
Bin Liu1, Weifeng Liu1, Renwu Jiang1
1Department of Burns and Plastic Surgery, Xiangtan Central Hospital, Xiangtan Hunan 411100, China.
Objective:
To observe clinical effects of combination of acellular porcine skin with delayed microskin graft on extensively burned patients. Methods: Forty extensively burned patients were assigned into a treatment group and a control group. In the treatment group, 20 patients were covered with acellular porcine skin after escharectomy, and the delayed microskin grafting was performed 5 days later. In the control group, 20 patients were covered with allograft skin combined with microskin graft after escharectomy. The cure rate, the graft survival rate, wound healing time and cost per 1% wound were observed. Results: The cure rate for the 2 groups was the same (90%), and wound healing time was similar between the two groups (P>0.05). The graft survival rate in the treatment group was higher than that in the control group (P<0.05), and cost per 1% wound in the treatment group was less than that in the control group (P<0.05). Conclusion: The combination of acellular porcine skin with delayed microskin graft is an effective method to treat extensively burned patients, and it provides an ideal substitute for allograft skin combined with microskin graft.
