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Detection of Toxin Translocation into the Host Cytosol by Surface Plasmon Resonance
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What Is the Link between Stringent Response, Endoribonuclease Encoding Type II Toxin-Antitoxin Systems and

Bhaskar C M Ramisetty1, Dimpy Ghosh2, Maoumita Roy Chowdhury2

  • 1School of Chemical and Biotechnology, SASTRA UniversityThanjavur, India; Department of Biochemistry and Molecular Biology, University of Southern DenmarkOdense, Denmark.

Frontiers in Microbiology
|December 10, 2016
PubMed
Summary

Bacterial persistence, a tolerance to antibiotics, is not linked to inorganic polyphosphate or ppGpp. Deleting toxin-antitoxin systems (TASs) in E. coli increases antibiotic sensitivity and reduces fitness, invalidating prior persistence studies.

Keywords:
fitnessinorganic polyphosphatepolar effectsppGpp

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