Related Experiment Video
Updated: Oct 13, 2026

Surgical Models of Gastroesophageal Reflux with Mice
Published on: August 25, 2015
Heartburn in Staff of Golestan Medical University, Northeast of Iran
Sima Besharat1, Mahsa Besharat1, Taghi Amiriani1
1Golestan University of Medical Sciences, Golestan Research center of Gastroenterology and Hepatology, Iran.
Insights
Heartburn, a common symptom of gastro-esophageal reflux disease (GERD), affected 60% of participants in Iran. This study found heartburn more prevalent in married women, suggesting further research into underlying causes.
Area of Science:
- Gastroenterology
- Epidemiology
- Public Health
Background:
- Gastro-esophageal reflux disease (GERD) is a prevalent gastrointestinal disorder with rising incidence in Iran and Asia.
- Key GERD symptoms include heartburn and acid regurgitation.
- Understanding GERD prevalence and risk factors in specific populations is crucial for public health initiatives.
Purpose of the Study:
- To investigate the prevalence of heartburn symptoms among personnel at Golestan Medical University.
- To identify potential demographic and lifestyle risk factors associated with heartburn in this population.
Main Methods:
- A cross-sectional study conducted in 2006 involving all personnel of Golestan Medical University.
- Data collection via questionnaires on demographics, symptoms, and risk factors; objective measurements of height and weight.
- Statistical analysis employed Chi-square and non-parametric tests to evaluate relationships between variables.
Main Results:
- Heartburn symptoms were reported by 60% of the 155 participants.
- No significant associations were found between heartburn and age, gender, BMI, or tribal affiliation.
- Heartburn symptoms were significantly more common in married individuals (P < 0.05).
Conclusions:
- The prevalence of heartburn in the studied population was notably high.
- Married individuals, particularly women, exhibited a higher incidence of heartburn.
- Further research is recommended to elucidate the underlying etiology and contributing factors for these observed patterns.
Background:
Gastro-esophageal reflux disease (GERD) is the most common gastrointestinal disease in the west that has shown increasing incidence in Iran and Asian countries. The main presentations, described for GERD, are heartburn and acid regurgitation.
Methods:
In this cross-sectional study in 2006, all personnel of Golestan Medical University (Northeast of Iran) were enrolled. A questionnaire consisting of demographic data, symptoms and risk factors was completed for all volunteers. Height and weight were measured. Chi-square and Non-parametric tests were used for analysis.
Results:
Symptoms of heartburn were seen in 60% of all 155 studied subjects. No significant relationship was seen between symptoms and variables like age, gender, BMI and tribes. Symptoms were more common in married ones (P < 0.05).
Conclusions:
Heartburn prevalence was high in this study. Heartburn was seen more in women and in married. The probable underlying etiology and explanation for these results should be studied more.
Related Concept Videos
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Peptic Ulcer Disease IV: Management
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current medication...
Upper GI Series: Barium Swallow
Purpose and Procedure
Patients undergoing this procedure ingest a liquid containing barium sulfate with a chalky...
Gastroesophageal Reflux Disease

