Related Experiment Video
Updated: Mar 10, 2026

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
Published on: October 28, 2021
Primary intracerebral osteosarcoma: a rare case report and review
Song-Ping Chen1, Jin-Long Tang2, Xiu-Liang Zhu3
1Department of Radiology, The People's Hospital of Zhenhai, No. 718 Naner West Road, Ningbo, 315202 Zhejiang China.
Background:
Primary intracranial osteosarcoma is a extremely rare disease entity. We describe a case of primary intracerebral osteosarcoma in an adult brain.
Case Description:
A patient who presented with a 1-week history of headaches, and MRI examination was performed. The immunohistochemical diagnosis confirmed primary intracerebral osteosarcoma. The patient was treated with a surgical resection of the tumor.
Conclusion:
Primary osteosarcomas occurring in the brain are extremely rare. The MRI images did not provide a specific pretreatment diagnosis, and the histopathology was the mainstay in establishing the diagnosis.

