Measurement of carotid pulse wave velocity using ultrafast ultrasound imaging in hypertensive patients

Xiaopeng Li1, Jue Jiang1, Hong Zhang1

  • 1Department of Ultrasound, The Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, No. 157, W. Fifth Road, Xincheng District, Xi'an, 710004, China.

Insights

Ultrafast ultrasound imaging effectively measures carotid pulse wave velocity (PWV) in hypertension patients. This technology shows promise for early detection of arterial issues in clinical practice.

Area of Science:

  • Cardiovascular Imaging
  • Hypertension Research
  • Vascular Ultrasound

Background:

  • Hypertension is a major risk factor for cardiovascular disease.
  • Early detection of arterial abnormalities is crucial for managing hypertension.
  • Carotid pulse wave velocity (PWV) is an indicator of arterial stiffness.

Purpose of the Study:

  • To evaluate the utility of ultrafast ultrasound imaging for measuring carotid PWV.
  • To assess carotid PWV and intima-media thickness (IMT) in newly diagnosed hypertension patients.
  • To explore the correlation between PWV, IMT, and hypertension stage.

Main Methods:

  • Prospective non-randomized study including 90 hypertensive patients and 50 healthy controls.
  • Carotid PWV (PWV-BS, PWV-ES) and IMT measured using ultrafast ultrasound imaging.
  • Spearman correlation analysis used to assess associations with hypertension stage.

Main Results:

  • Hypertensive patients exhibited significantly elevated PWV-BS and PWV-ES compared to controls.
  • PWV-BS and PWV-ES increased with hypertension stage.
  • PWV-BS, PWV-ES, and IMT showed a positive correlation with hypertension stage.

Conclusions:

  • Ultrafast ultrasound imaging is a valid and convenient method for carotid PWV measurement in hypertensive patients.
  • This technique may serve as a promising tool for early detection of arterial abnormalities.
  • The findings support the use of ultrafast ultrasound for routine clinical assessment in hypertension.
Abstract