Related Experiment Video
Updated: Mar 10, 2026

Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging
Published on: February 7, 2014
Measurement of carotid pulse wave velocity using ultrafast ultrasound imaging in hypertensive patients
Xiaopeng Li1, Jue Jiang1, Hong Zhang1
1Department of Ultrasound, The Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, No. 157, W. Fifth Road, Xincheng District, Xi'an, 710004, China.
Insights
Ultrafast ultrasound imaging effectively measures carotid pulse wave velocity (PWV) in hypertension patients. This technology shows promise for early detection of arterial issues in clinical practice.
Area of Science:
- Cardiovascular Imaging
- Hypertension Research
- Vascular Ultrasound
Background:
- Hypertension is a major risk factor for cardiovascular disease.
- Early detection of arterial abnormalities is crucial for managing hypertension.
- Carotid pulse wave velocity (PWV) is an indicator of arterial stiffness.
Purpose of the Study:
- To evaluate the utility of ultrafast ultrasound imaging for measuring carotid PWV.
- To assess carotid PWV and intima-media thickness (IMT) in newly diagnosed hypertension patients.
- To explore the correlation between PWV, IMT, and hypertension stage.
Main Methods:
- Prospective non-randomized study including 90 hypertensive patients and 50 healthy controls.
- Carotid PWV (PWV-BS, PWV-ES) and IMT measured using ultrafast ultrasound imaging.
- Spearman correlation analysis used to assess associations with hypertension stage.
Main Results:
- Hypertensive patients exhibited significantly elevated PWV-BS and PWV-ES compared to controls.
- PWV-BS and PWV-ES increased with hypertension stage.
- PWV-BS, PWV-ES, and IMT showed a positive correlation with hypertension stage.
Conclusions:
- Ultrafast ultrasound imaging is a valid and convenient method for carotid PWV measurement in hypertensive patients.
- This technique may serve as a promising tool for early detection of arterial abnormalities.
- The findings support the use of ultrafast ultrasound for routine clinical assessment in hypertension.
Purpose:
The study aimed to assess the utility of ultrafast ultrasound imaging for evaluation of carotid pulse wave velocity (PWV) in newly diagnosed hypertension patients.
Methods:
This prospective non-randomized study enrolled 90 hypertensive patients in our hospital from September to December 2013 as a hypertension group. An age- and sex-matched cohort of 50 healthy adults in our hospital from September to December 2013 was also included in the study as a control group. Carotid PWV at the beginning and at the end of systole (PWV-BS and PWV-ES, respectively) and intima-media thickness (IMT) were measured by ultrafast ultrasound imaging technology. The associations of PWV-BS, PWV-ES, and IMT with hypertension stage were evaluated by Spearman correlation analysis.
Results:
PWV-BS and PWV-ES in the hypertension group were significantly elevated compared with those in control group. Different hypertension stages significantly differed in PWV-BS and PWV-ES. PWV-BS and PWV-ES appeared to increase with the hypertension stage. Moreover, IMT, PWV-BS, and PWV-ES were positively correlated with the hypertension stage in hypertensive patients.
Conclusion:
Ultrafast ultrasound imaging was a valid and convenient method for the measurement of carotid PWV in hypertensive patients. Ultrafast ultrasound imaging might be recommended as a promising alternative method for early detection of arterial abnormality in clinical practice.
Related Concept Videos
Assessing Blood pressure using a doppler ultrasound
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Pulse
The pulse serves as a clinical...

