[Long-term HRV analysis shows stress reduction by magnesium intake]

Area of Science:

• Cardiology
• Neuroscience
• Nutritional Science

Background:

• Mental pressure and stress are significant societal challenges.
• Heart rate variability (HRV) reflects neurovegetative activity; low HRV indicates stress.
• Magnesium is a vital mineral with potential cardiovascular benefits.

Purpose of the Study:

• To investigate the effect of magnesium supplementation combined with strength-endurance training on sympathovagal balance.
• To assess changes in HRV parameters as indicators of stress and nervous system regulation.
• To examine the impact on intracellular magnesium concentration.

Main Methods:

• A 90-day randomized controlled study with 100 participants.
• Two arms: one receiving daily magnesium (400 mg) plus training, the other control (training only).
• Measurement of HRV parameters (pNN50, LF-HF ratio, stress index) and intracellular magnesium.

Main Results:

• Magnesium group showed significant improvements in HRV parameters, including increased parasympathetic activity (pNN50).
• The LF-HF ratio and stress index decreased in the magnesium group, indicating better autonomic balance.
• No significant changes in HRV were observed in the control group; intracellular magnesium levels remained unaffected.

Conclusions:

• Daily magnesium intake benefits individuals experiencing mental and physical stress.
• Magnesium supplementation may enhance physiological regulation of the autonomic nervous system.
• Adequate magnesium may help prevent stress-related symptoms like sleep disturbances and irritability.