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Updated: Mar 10, 2026

Preparation and Use of Carbonyl-decorated Carbenes in the Activation of White Phosphorus
Published on: October 3, 2014
Cobalt-Catalyzed Carbonylation of C(sp2)-H Bonds with Azodicarboxylate as the Carbonyl Source
Jiabin Ni1,2, Jie Li1,3, Zhoulong Fan1,2
1CAS Key Laboratory of Receptor Research, and Synthetic Organic & Medicinal Chemistry Laboratory (SOMCL), Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences , Shanghai 201203, China.
Abstract:
A novel and efficient approach for the C(sp2)-H bond carbonylation of benzamides has been developed using stable and inexpensive Co(OAc)2·4H2O as the catalyst and the commercially available and easily handling azodicarboxylates as the nontoxic carbonyl source. A broad range of substrates bearing diverse functional groups were tolerated. This is the first example where cobalt-catalyzed C(sp2)-H bond carbonylation occurs with azodicarboxylate as the carbonyl source.
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