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Characterization and Prediction of Cardiovascular Effects of Fingolimod and Siponimod Using a Systems Pharmacology

Nelleke Snelder1, Bart A Ploeger1, Olivier Luttringer1

  • 1Division of Pharmacology, Leiden Academic Centre for Drug Research, Leiden, The Netherlands (N.S., B.A.P., M.D.); LAP&P Consultants BV, Leiden, The Netherlands (N.S., M.D.); Modeling and Simulation Department, Novartis, Basel, Switzerland (O.L., D.R.S.); Cardiovascular and Metabolism Research, Novartis Institutes for BioMedical Research (D.F.R., D.F., F.F., M.B., L.J.), and Cardiovascular Clinical Development (R.L.W.), Novartis Pharmaceuticals Corporation, East Hanover, New Jersey.

The Journal of Pharmacology and Experimental Therapeutics
|December 10, 2016
PubMed

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