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Xurography for microfluidics on a reactive solid.

Amélie Neuville1, Louis Renaud2, Thi Thuy Luu3

  • 1International Research Institute of Stavanger, PO Box 8046, 4068 Stavanger, Norway. amelie.neuville@fys.uio.no and Condensed Matter Physics group, Physics Department, University of Oslo, PO Box 1048 Blindern, 0316 Oslo, Norway.

Lab on a Chip
|December 10, 2016
PubMed
Summary

We developed a microfluidic method to measure material dissolution rates in situ. This technique quantizes the dissolution of calcite windows using advanced microscopy and controlled fluid flow.

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Area of Science:

  • Materials Science
  • Chemical Engineering
  • Geochemistry

Background:

  • In situ monitoring of reactive material dissolution is crucial for understanding chemical processes.
  • Traditional methods often lack the resolution or control needed for precise kinetic studies.
  • Microfluidic systems offer a controlled environment for studying dynamic material interactions.

Purpose of the Study:

  • To present a novel microfluidic cell design for in situ observation of transparent reactive material dissolution.
  • To determine the dissolution rate of optical-quality calcite in aqueous solutions.
  • To demonstrate the utility of the method for kinetic studies.

Main Methods:

  • Fabrication of microfluidic channels using xurography with double-sided tape.
  • Embedding transparent reactive materials (calcite windows) within the microfluidic cell.
  • In situ topographic measurement using interference microscopy (4.9 μm pixel, 50 nm vertical resolution).
  • Controlled circulation of fluids (water, hydrochloric acid) at defined flow rates.
  • Application of a photoresist layer to mitigate inlet/outlet effects and serve as a reference.

Main Results:

  • Successfully measured the in situ dissolution of calcite windows.
  • Quantified the dissolution rate of calcite in water and hydrochloric acid solutions.
  • Demonstrated the feasibility of observing material topography changes over time (10 s intervals).
  • Validated the use of photoresist for stabilizing reactive interfaces and providing a reference surface.

Conclusions:

  • The proposed microfluidic method enables precise, in situ measurement of reactive material dissolution rates.
  • This technique is suitable for studying the kinetics of optically transparent materials under controlled conditions.
  • The method provides a valuable tool for materials science, geochemistry, and chemical engineering applications.