Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transient perinuclear actin rings prevent cell aging and apoptosis via nuclear mechanical protection.

Biophysical journal·2026
Same author

Force loading on molecular clutches governs the stability of cell lamellipodia.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Influence of body composition on short- and long-term clinical outcomes in patients undergoing laparoscopic gastrectomy.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026
Same author

Nucleoplasmic ZNF467 condensates boost hematopoietic stem cell engraftment via ICAM1-mediated mechanical reprogramming.

Blood·2026
Same author

Transient mechanical activation of the Piezo1 channel facilitates ex vivo expansion of hematopoietic stem cells.

Cell research·2026
Same author

Targeting leukemic stem cell biomechanics suppresses stemness and enhances NK cell-mediated immunotherapy.

Nature communications·2025

Related Experiment Video

Updated: Mar 10, 2026

AC Electrokinetic Phenomena Generated by Microelectrode Structures
20:38

AC Electrokinetic Phenomena Generated by Microelectrode Structures

Published on: July 28, 2008

12.0K

A novel micromixer based on the alternating current-flow field effect transistor.

Yupan Wu1, Yukun Ren2, Ye Tao1

  • 1School of Mechatronics Engineering, Harbin Institute of Technology, West Da-zhi Street 92, Harbin, Heilongjiang, 150001 PR China. rykhit@hit.edu.cn.

Lab on a Chip
|December 10, 2016
PubMed
Summary

We introduce a novel AC-flow FET (AC-FFET) for efficient microfluidic mixing using induced-charge electroosmosis (ICEO). This simple, low-energy device utilizes a floating electrode as a gate to control ICEO flow for enhanced mixing performance.

More Related Videos

Electrotaxis Studies of Lung Cancer Cells using a Multichannel Dual-electric-field Microfluidic Chip
08:35

Electrotaxis Studies of Lung Cancer Cells using a Multichannel Dual-electric-field Microfluidic Chip

Published on: December 29, 2015

9.2K
Designing Microfluidic Devices for Studying Cellular Responses Under Single or Coexisting Chemical/Electrical/Shear Stress Stimuli
10:35

Designing Microfluidic Devices for Studying Cellular Responses Under Single or Coexisting Chemical/Electrical/Shear Stress Stimuli

Published on: August 13, 2016

9.4K

Related Experiment Videos

Last Updated: Mar 10, 2026

AC Electrokinetic Phenomena Generated by Microelectrode Structures
20:38

AC Electrokinetic Phenomena Generated by Microelectrode Structures

Published on: July 28, 2008

12.0K
Electrotaxis Studies of Lung Cancer Cells using a Multichannel Dual-electric-field Microfluidic Chip
08:35

Electrotaxis Studies of Lung Cancer Cells using a Multichannel Dual-electric-field Microfluidic Chip

Published on: December 29, 2015

9.2K
Designing Microfluidic Devices for Studying Cellular Responses Under Single or Coexisting Chemical/Electrical/Shear Stress Stimuli
10:35

Designing Microfluidic Devices for Studying Cellular Responses Under Single or Coexisting Chemical/Electrical/Shear Stress Stimuli

Published on: August 13, 2016

9.4K

Area of Science:

  • Microfluidics
  • Electrokinetics
  • Nanotechnology

Background:

  • Induced-charge electroosmosis (ICEO) is a key phenomenon for microfluidic pumping and mixing.
  • Existing ICEO methods often require complex structures or high energy consumption.
  • Developing efficient and simple microfluidic mixers remains a significant challenge.

Purpose of the Study:

  • To propose and investigate a novel microfluidic mixer based on fixed-potential ICEO flow around a floating electrode.
  • To demonstrate the application of an AC-flow FET (AC-FFET) concept for generating asymmetric ICEO flow for mixing.
  • To evaluate the mixing efficiency and performance enhancement strategies for the proposed AC-FFET micromixer.

Main Methods:

  • Fabrication of a microfluidic device with a tandem electrode configuration on glass substrates.
  • Utilizing a floating electrode as a gate to control ICEO flow, analogous to a field-effect transistor (FET).
  • Conducting mixing experiments and comparing results with simulations to validate performance.

Main Results:

  • The AC-FFET device demonstrated efficient microfluidic mixing capabilities.
  • Asymmetric vortexes were generated using the tandem electrode configuration, leading to effective mixing.
  • Mixing performance was enhanced by optimizing the phase difference between electrodes and using square wave signals.

Conclusions:

  • The AC-FFET offers a simple and effective solution for microfluidic mixing.
  • The device exhibits low-energy consumption and can be manufactured using cost-effective processes.
  • This approach provides a promising alternative for addressing mixing challenges in microfluidic systems.