Related Experiment Video
Updated: Mar 10, 2026

A Reporter Assay to Analyze Intronic microRNA Maturation in Mammalian Cells
Published on: June 16, 2022
RETRACTED: MicroRNA138 regulates keratin 17 protein expression to affect HaCaT cell proliferation and apoptosis by
Shi-Jun Feng1, Rui-Qi Chu2, Jing Ma1
1Department of Dermatology, Cangzhou Central Hospital, Cangzhou 061001, PR China.
Abstract:
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. An Expression of Concern for this article was previously published while an investigation was conducted (see related editorial: https://doi.org/10.1016/j.biopha.2022.113812). This retraction notice supersedes the Expression of Concern published earlier. Concern was raised about the reliability of the flow cytometry data in Figure 9, with suspected image similarities reported between the ‘miR-138 mimic’ and ‘siRNA hTERT’ groups, as detailed here: https://pubpeer.com/publications/983120063E7603EBA705B85BBF77F5; and here: https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249. Independent analysis confirmed this finding and identified additional suspected image duplications within Figure 9. The journal requested the corresponding author comment on these concerns and provide the associated raw data. The authors did not respond to this request and therefore the Editor-in-Chief decided to retract the article.
Related Concept Videos
MicroRNAs
MicroRNAs
mTOR Signaling and Cancer Progression
The mTOR pathway or the...
PI3K/mTOR/AKT Signaling Pathway
MAPK Signaling Cascades
Hedgehog Signaling Pathway

