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In-vitro evaluation of antibiotic combinations against Campylobacter fetus
H Goossens1, H Coignau, L Vlaes
1WHO Collaborating Centre for Enteric Campylobacter, St Pieters University Hospital, Brussels, Belgium.
The Journal of Antimicrobial Chemotherapy
|August 1, 1989
Abstract:
We evaluated the in-vitro activity of 16 antibiotics against 22 clinical isolates of Campylobacter fetus. The interaction of these antibiotics was also tested by chequer-board titration and time-kill assay. Eight antibiotic combinations were evaluated. Antagonism was not found with any of the combinations tested. The highest synergistic effect was obtained with a combination of ampicillin and cefazolin or ampicillin and gentamicin.