Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Journal Bearings

Journal Bearings

Journal bearings are mechanical components that support and provide lateral stability to rotating shafts and axles. They are crucial in reducing friction, wear, and vibration in machinery such as engines, turbines, and pumps. The principle behind journal bearings is forming a thin lubricant film between the bearing surface and the rotating shaft, which minimizes direct contact and reduces frictional forces.
To better understand the concept of journal bearings, consider a rope winch with dry or...

Life Histories

Life Histories

Tissues

Tissues

Cells with similar structure and function are grouped into tissues. A group of tissues with a specialized function is called an organ. There are four main types of tissue in vertebrates: epithelial, connective, muscle, and nervous.

Dietary Connections

Dietary Connections

In biological systems, most metabolic pathways are interconnected. The cellular respiration processes that convert glucose to ATP—such as glycolysis, pyruvate oxidation, and the citric acid cycle—tie into those that break down other organic compounds. As a result, various foods—from apples to cheese to guacamole—end up as ATP. In addition to carbohydrates, food also contains proteins and lipids—such as cholesterol and fats. All of these organic compounds are used...

Internal Receptors

Internal Receptors

Many cellular signals are hydrophilic and therefore cannot pass through the plasma membrane. However, small or hydrophobic signaling molecules can cross the hydrophobic core of the plasma membrane and bind to internal, or intracellular, receptors that reside within the cell. Many mammalian steroid hormones use this mechanism of cell signaling, as does nitric oxide (NO) gas.

The Scientific Method

The Scientific Method

The scientific method is a detailed, empirical problem-solving process used by biologists and other scientists. This iterative approach involves formulating a question based on observation, developing a testable potential explanation for the observation (called a hypothesis), making and testing predictions based on the hypothesis, and using the findings to create new hypotheses and predictions.
Generally, predictions are tested using carefully-designed experiments. Based on the outcome of these...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Short communication: Relationship between methods for measurement of serum electrolytes and the relationship between ionized and total calcium and neutrophil oxidative burst activity in early postpartum dairy cows.

Journal of dairy science·2017

Same author

From the Journals.

Journal of wound care·2016

Same author

Topical Antimicrobial Agents in Wound Care.

Journal of wound care·2016

Same author

From the Journals.

Journal of wound care·2016

Same author

From the Journals.

Journal of wound care·2016

Same author

From the Journals.

Journal of wound care·2016

Same journal

Journal of wound care·2026

Same journal

Journal of wound care·2026

Same journal

Journal of wound care·2026

Same journal

Journal of wound care·2026

Same journal

Journal of wound care·2026

Same journal

Journal of wound care·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 10, 2026

The ITS2 Database

The ITS2 Database

Published on: March 12, 2012

From the Journals.

J C Lawrence¹, J C Lawrence¹

¹Senior Research Fellow, Wound Healing Research Unit, Cardiff.

Journal of Wound Care

|December 13, 2016

Summary

This summary is machine-generated.

Systemic antibiotics offer new hope for chronic wound healing by combating infection. Advances in antimicrobial therapy are crucial for improving patient outcomes in wound care.

More Related Videos

In Silico Clinical Trials for Cardiovascular Disease

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

In vivo and In vitro Rearing of Entomopathogenic Nematodes Steinernematidae and Heterorhabditidae

In vivo and In vitro Rearing of Entomopathogenic Nematodes Steinernematidae and Heterorhabditidae

Published on: September 22, 2014

Related Experiment Videos

Last Updated: Mar 10, 2026

The ITS2 Database

The ITS2 Database

Published on: March 12, 2012

In Silico Clinical Trials for Cardiovascular Disease

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

In vivo and In vitro Rearing of Entomopathogenic Nematodes Steinernematidae and Heterorhabditidae

In vivo and In vitro Rearing of Entomopathogenic Nematodes Steinernematidae and Heterorhabditidae

Published on: September 22, 2014

Area of Science:

Infectious Diseases
Dermatology
Pharmacology

Background:

Chronic wounds pose a significant challenge in healthcare, often complicated by persistent bacterial infections.
Systemic antibiotics are frequently used, but resistance and efficacy remain concerns.

Purpose of the Study:

To review new developments in systemic antibiotic therapy for chronic wounds.
To discuss the implications of these advancements for clinical wound care practices.

Main Methods:

Literature review of recent studies on systemic antibiotics and antimicrobial therapies.
Analysis of clinical trial data and expert consensus on wound infection management.

Main Results:

Emerging antibiotic classes show promise against resistant pathogens.
Pharmacokinetic/pharmacodynamic (PK/PD) optimization is key for effective treatment.
Combination therapies may enhance efficacy and reduce resistance.

Conclusions:

New antimicrobial strategies are vital for overcoming challenges in chronic wound treatment.
Personalized approaches integrating novel therapies are essential for improved wound healing and patient care.